|
KMID : 1144820210270030161
|
|
대한의생명과학회지
2021 Volume.27 No. 3 p.161 ~ p.169
|
|
|
Antioxidant and Anti-inflammatory Effects of Hot Water and Ethanol Extracts from Endemic Plants in Indonesia
|
|
Hwang Jin-Woo
Choi Jae-Ho
Kang Sang-Moon
Lee Sung-Gyu
Kang Hyun
|
|
|
Abstract
|
|
|
|
The present study, antioxidant and anti-inflammatory effects were measured of 6 endemic plants in Indonesian extracted by hot water or ethanol. The Nipa Fruticans Wurmb ethanol extract (NFWE) and Orthosiphon aristatus ethanol extract (OAE) showed the highest polyphenol and flavonoid contents of 203.70 and 33.70 μg/mg, respectively. Antioxidant activity of OAE was highest in DPPH radical scavenging activity (77.49% at 10 μg/mL) and ABTS+ radical scavenging activity (93.36% at 10 μg/mL). FRAP activity was significantly higher in NFWE than other extracts. Anti-inflammatory effects of 6 endemic plants in Indonesian extracted by hot water or ethanol were examined using nitric oxide (NO) inhibition assays. In the LPS-induced BV2 cells, OAE showed the highest inhibition of NO production without toxicity. The results of this study, suggest that OAE is a potential functional raw material for antioxidant and anti-inflammatory.
|
|
|
KEYWORD
|
|
|
Indonesia, Plants, Antioxidant, Anti-inflammatory, Cytotoxicity
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|